Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965758 | 0.98 | CYP1A2 (0.45) | CYP1A2GAAALDH1A1ALOX15TSHR | |
| Methylene Chloride SCHEMBL28551225 | 0.91 | CYP1A2 (0.41) | CYP1A2GAAALDH1A1HTTPIK3CA | |
| SCHEMBL8844371 | 0.84 | GAA (0.47) | CYP1A2GAAALDH1A1TSHRHTT | |
| SCHEMBL329417 | 0.82 | CYP1A2 (0.52) | CYP1A2GAAALDH1A1ALOX15TSHR | |
| SCHEMBL8795 | 0.82 | CYP1A2 (0.52) | CYP1A2GAAALDH1A1ALOX15TSHR | |
| SCHEMBL1131131 | 0.79 | GAA (0.47) | CYP1A2GAAALDH1A1TSHRHTT | |
| SCHEMBL802854 | 0.79 | — | — | |
| SCHEMBL9433260 | 0.73 | POLB (0.40) | CYP1A2ALDH1A1TSHR | |
| SCHEMBL12393233 | 0.73 | TSHR (0.35) | TSHR | |
| SCHEMBL94294 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355385-B1 | SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5091529-A | HERBICIDAL SUBSTITUTED SULPHONYLAMINOAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-5021082-A | Pre=and postemergent | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0419831-A2 | Substituted sulfonylaminoazoles | BAYER AG (DE) | 1991-04-03 | — | — | EP | disclosed |
| EP-0384250-A2 | Sulfonylated azinyliminoheteroazole, process and intermediates for their preparation and their use as herbicides | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |
| US-4941912-A | Herbicidal substituted sulphonylaminoazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0355385-A1 | Substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones, process and intermediates for their preparation and their use as herbicides | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| EP-0330959-A2 | Substituted sulphonyl amino azoles | BAYER AG (DE) | 1989-09-06 | — | — | EP | disclosed |