Sugi Predict

Sugi Predict / Compounds / SCHEMBL329417

SCHEMBL329417

SCHEMBL329417

COc1nc(Cl)nc(Cl)n1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.52
▸ ALDH1A1 P00352 6/20 0.50
▸ TSHR P16473 2/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ MAPT P10636 4/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ ATM Q13315 2/20 0.34
▸ HTT P42858 2/20 0.34
▸ RECQL P46063 1/20 0.34
▸ SMN1; SMN2 Q16637 4/20 0.34
▸ GAA P10253 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.32
▸ MAT2A P31153 1/20 0.32
▸ HSP90AA1 P07900 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8795 0.94 CYP1A2 (0.52) CYP1A2ALDH1A1TSHRALOX15MAPT
SCHEMBL1965758 0.84 CYP1A2 (0.45) CYP1A2ALDH1A1TSHRALOX15MAPT
SCHEMBL9190048 0.82 CYP1A2 (0.44) CYP1A2ALDH1A1TSHRALOX15
SCHEMBL9529398 0.82 CYP1A2 (0.44) CYP1A2ALDH1A1TSHRALOX15HTT
SCHEMBL1577050 0.82 HSP90AA1 (0.50) CYP1A2ALDH1A1TSHRALOX15MAPT
SCHEMBL2633403 0.82 CYP1A2 (0.44) CYP1A2ALDH1A1TSHRALOX15LMNA
SCHEMBL32665731 0.80 CYP1A2 (0.42) CYP1A2ALDH1A1TSHRALOX15MAPT
SCHEMBL14569431 0.80 CYP1A2 (0.42) CYP1A2ALDH1A1TSHRALOX15MAPT
SCHEMBL9432115 0.78 CYP1A2 (0.41) CYP1A2CYP2C19LMNA
SCHEMBL9402313 0.78 POLB (0.43) CYP1A2ALDH1A1TSHRMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 943 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121779704-B Triazine polymer, high-temperature-resistant carbon fiber sizing agent, preparation method and application SICHUAN UNIVERSITY (CN) 2026-05-26 — — CN claimed
US-12344589-B2 Method for producing a 1,5-benzothiazepin compound ELOBIX AB (SE) 2025-07-01 — — US claimed
CN-120192545-A Metal main chain macromolecule based on triazine compound and synthetic method thereof 复旦大学 2025-06-24 — — CN claimed
CN-119775560-A Polymeric resin and preparation method and application thereof 珠海莫界科技有限公司 2025-04-08 — — CN claimed
CN-119225053-A Maintenance and detection system for liquid crystal display module 深圳市畅思得电子设备维护有限公司 2024-12-31 — — CN claimed
US-12084570-B2 Chitosan as an intumescing, thermoformable flame retardant AMERICAN UNIVERSITY (US) 2024-09-10 — — US claimed
CN-118554392-A DCMT differential protection method based on additional bridge arm current measurement 四川大学 2024-08-27 — — CN claimed
CN-117695872-B Composite membrane group for membrane extraction-membrane back extraction and preparation method and application thereof 中国海洋大学 2024-07-19 — — CN claimed
CN-118138107-A Construction method of inter-satellite antenna link pointing algorithm 长光卫星技术股份有限公司 2024-06-04 — — CN claimed
CN-117695872-A Composite membrane group for membrane extraction-membrane back extraction and preparation method and application thereof 中国海洋大学 2024-03-15 — — CN claimed
US-20070037986-A1 reacting N-methyl-o-phenylenediamine with 2-propyl-4-methyl-1H-benzimidazole-6-carboxylic acid, coupling and cyclization is achieved using 1,3,5-triazine ( 2-chloro-4,6-dimethoxy-1,3,5-triazine) and tertiary amine ( morpholine, N-methyl-) BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2007-02-15 — — US claimed
WO-2007009967-A1 PREPARATION OF 1,7′-DIMETHYL-2′-PROPYL-2,5′-BI-1H-BENZIMIDAZOLE BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2007-01-25 — — WO claimed
US-5667976-A AMINE POLYMER COATING BECTON DICKINSON AND COMPANY (US) 1997-09-16 — — US claimed
WO-1994000600-A1 SOLID SUPPORTS FOR NUCLEIC ACID HYBRIDIZATION ASSAYS MICROPROBE CORPORATION (US) 1994-01-06 — — WO claimed
EP-0380017-A2 A process for the preparation of triazinic polymers HIMONT ITALIA S.r.l. (IT) 1990-08-01 — — EP claimed
US-4705746-A Photographic polyolefin coated paper FUJI PHOTO FILM CO., LTD. (JP) 1987-11-10 — — US claimed
EP-0038154-B1 ALLERGENS MODIFIED WITH POLYSARCOSINES BEECHAM GROUP PLC (GB) 1983-09-21 — — EP claimed
EP-0012716-B1 MONOCHLOROTRIAZINE DYESTUFFS OF THE PYRAZOLONE SERIES, THEIR PREPARATION AND THEIR USE FOR DYEING AND PRINTING TEXTILE MATERIALS CIBA-GEIGY AG (CH) 1983-06-15 — — EP claimed
EP-0038154-A1 Allergens modified with polysarcosines BEECHAM GROUP PLC (GB) 1981-10-21 — — EP claimed
EP-0012716-A1 Monochlorotriazine dyestuffs of the pyrazolone series, their preparation and their use for dyeing and printing textile materials CIBA-GEIGY AG (CH) 1980-06-25 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070037986-A1 reacting N-methyl-o-phenylenediamine with 2-propyl-4-methyl-1H-benzimidazole-6-carboxylic acid, coupling and cyclization is achieved using 1,3,5-triazine ( 2-chloro-4,6-dimethoxy-1,3,5-triazine) and tertiary amine ( morpholine, N-methyl-) PNMT, PAM, PAH CYP1A2 66/4885ALDH1A1 1278/4885TSHR 1460/4885
US-12344589-B2 Method for producing a 1,5-benzothiazepin compound CYP3A5, KCNJ5, KCNK5 CYP1A2 112/4885ALDH1A1 758/4885TSHR 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.