Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6669418 | 0.99 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPTCHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL30038061 | 0.99 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPTCHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL720051 | 0.98 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTCHRM2CHRM1CHRM3 | |
| SCHEMBL9531097 | 0.76 | GLA (0.41) | CHRM2CHRM1NTMT1CYP2D6MEN1 | |
| SCHEMBL9529955 | 0.75 | CHRM2 (0.41) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9529931 | 0.74 | CHRM2 (0.40) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9529193 | 0.74 | CHRM2 (0.38) | CHRM2CHRM1CHRM3CHRM4NTMT1 | |
| SCHEMBL9529572 | 0.74 | CHRNA7 (0.36) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9529197 | 0.73 | CHRNA7 (0.36) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9529691 | 0.73 | ALDH1A1 (0.39) | MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | claimed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | claimed |