Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CFB | P00751 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886773 | 0.75 | CCR8 (0.52) | CCR8KMT2AHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL9569229 | 0.73 | CCR8 (0.30) | CCR8 | |
| SCHEMBL9262366 | 0.73 | KDM4E (0.46) | KMT2AHSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL21050882 | 0.71 | CCR8 (0.47) | CCR8KMT2AHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL9569212 | 0.71 | — | — | |
| SCHEMBL29431923 | 0.70 | ALK (0.38) | KMT2AHSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL29974781 | 0.64 | CCR8 (0.46) | CCR8KMT2AHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL21050814 | 0.64 | CCR8 (0.46) | CCR8KMT2AHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL240017 | 0.62 | CA12 (0.44) | KMT2AHSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10587891 | 0.61 | ALDH1A1 (0.55) | CCR8KMT2AHSD17B10SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533904-A1 | NOVEL DIFLUORINATED QUINOLONES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | BOUCHARA S.A. (FR) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992018497-A1 | NOVEL DIFLUORINATED QUINOLONES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | BOUCHARA S.A. (FR) | 1992-10-29 | — | — | WO | disclosed |