⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128316 | 0.71 | — | — | |
| SCHEMBL750708 | 0.71 | — | — | |
| SCHEMBL2487462 | 0.71 | — | — | |
| Iodide SCHEMBL27887241 | 0.69 | — | — | |
| Bromide SCHEMBL27485582 | 0.69 | — | — | |
| SCHEMBL10762229 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL11308925 | 0.69 | — | — | |
| SCHEMBL19823606 | 0.67 | HRH1 (0.34) | — | |
| SCHEMBL7250091 | 0.67 | — | — | |
| SCHEMBL1545511 | 0.67 | GAA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230543-A1 | INDOLIZINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023230540-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2020249664-A1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-12-17 | — | — | WO | disclosed |
| EP-3142638-B1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | OREAL (FR) | 2020-08-12 | — | — | EP | disclosed |
| US-10604506-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| CN-105732859-B | Sulfur-tail-end-containing polymer and preparation method thereof | 中国石油天然气股份有限公司 | 2018-06-01 | — | — | CN | disclosed |
| EP-2113011-B1 | DISPERSE DYES, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DISTRIB GMBH (DE) | 2018-02-21 | — | — | EP | disclosed |
| US-9738634-B2 | Heterocyclic amide compound and herbicide | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-22 | — | — | US | disclosed |
| CN-105732859-A | Sulfur-tail-end-containing polymer and preparation method thereof | 中国石油天然气股份有限公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-103519109-A | Natural flavor blending material | ZHENG YUNCAI | 2014-01-22 | — | — | CN | disclosed |
| CN-100352505-C | Combination of FBP enzyme inhibitors and insulin sensitizers for the treatment of diabetes | METABASIS THERAPEUTICS INC (US) | 2007-12-05 | — | — | CN | disclosed |
| CN-1714866-A | A combination of fbpase inhibitors and insulin sensitizers for the treatment of diabetes | METABASIS THERAPEUTICS INC (US) | 2006-01-04 | — | — | CN | disclosed |
| CN-1599612-A | Combination of FBP enzyme inhibitor and antidiabetic agent for treating diabetes | METABASIS THERAPEUTICS INC (US) | 2005-03-23 | — | — | CN | disclosed |
| CN-1434828-A | Novel bisaminophosphonate prodrugs | METABASIS THERAPEUTICS INC (US) | 2003-08-06 | — | — | CN | disclosed |
| CN-1350466-A | Combination of FBP enzyme inhibitors and insulin sensitizers for the treatment of diabetes | METABASIS THERAPEUTICS INC (US) | 2002-05-22 | — | — | CN | disclosed |
| EP-0544705-A1 | DERIVATIVES OF MUPIROCIN | Beecham Group p.l.c. (GB) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992002518-A1 | DERIVATIVES OF MUPIROCIN | BEECHAM GROUP PLC (GB) | 1992-02-20 | — | — | WO | disclosed |
| US-4683227-A | CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0211526-A2 | Cephalosporins, their preparation and formulations | ELI LILLY AND COMPANY (US) | 1987-02-25 | — | — | EP | disclosed |
| CN-86104690-A | The method for preparing the cynnematin of 7 β-heteroaryl amido-3-chloro-replacement | — | 1987-01-21 | — | — | CN | disclosed |