Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9527991 | 0.98 | CHRNA7 (0.54) | CHRNA7SLC18A3HTTSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9532863 | 0.73 | HTR2C (0.43) | — | |
| SCHEMBL3217359 | 0.72 | CHRNA7 (1.00) | CHRNA7LMNA | |
| SCHEMBL11558947 | 0.70 | SLC18A3 (0.58) | CHRNA7SLC18A3HTTSLC6A2SLC6A4 | |
| SCHEMBL11105295 | 0.70 | SLC6A2 (0.54) | CHRNA7SLC18A3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL463706 | 0.70 | SLC18A3 (0.58) | CHRNA7SLC18A3HTTSLC6A2SLC6A4 | |
| SCHEMBL11558939 | 0.70 | SLC18A3 (0.58) | CHRNA7SLC18A3HTTSLC6A2SLC6A4 | |
| SCHEMBL10964462 | 0.70 | SLC6A2 (0.54) | CHRNA7SLC18A3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11562671 | 0.70 | SLC18A3 (0.58) | CHRNA7SLC18A3HTTSLC6A2SLC6A4 | |
| SCHEMBL11105288 | 0.70 | SLC6A2 (0.54) | CHRNA7SLC18A3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | claimed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | claimed |