Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529654 | 0.84 | ESR2 (0.32) | — | |
| SCHEMBL9531972 | 0.82 | HTR2C (0.44) | HTR2CHRH1CNR2 | |
| SCHEMBL9531304 | 0.82 | NISCH (0.35) | — | |
| SCHEMBL7439313 | 0.80 | MAOB (0.46) | HTR2CHRH1HRH4SCN2AKDM1A | |
| SCHEMBL8540798 | 0.79 | HTR2C (0.44) | HTR2CHRH1HRH4SCN2AGRIN1 | |
| SCHEMBL7435086 | 0.79 | HTR2C (0.49) | HTR2CHRH1HRH4SCN2AGRIN1 | |
| SCHEMBL9875803 | 0.78 | HTR2C (0.41) | HTR2C | |
| SCHEMBL7100010 | 0.77 | HTR2C (0.43) | HTR2CHRH1HRH4SCN2A | |
| SCHEMBL8541203 | 0.76 | HTR2C (0.42) | HTR2CHRH1HRH4 | |
| Hydrochloric Acid SCHEMBL1742023 | 0.76 | HTR2C (0.44) | HTR2CHRH1HRH4SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |