Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10559488 | 1.00 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL4399146 | 1.00 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL9579065 | 0.93 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL2772386 | 0.87 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL11423947 | 0.87 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL7797173 | 0.87 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL28887982 | 0.87 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL8479039 | 0.85 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL10797452 | 0.85 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL11784718 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355516-A | Small molecules for the treatment of kinase-related diseases | 阿索斯治疗公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4866064-A | AGRICULTURE HORTICULTURE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |