Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298306 | 0.86 | NPSR1 (0.68) | NPSR1BRD4ALOX15IRAK4RAB9A | |
| SCHEMBL6793428 | 0.85 | NPSR1 (0.77) | NPSR1BRD4ALOX15IRAK4RAB9A | |
| Bromide SCHEMBL9297499 | 0.85 | NPSR1 (0.66) | NPSR1BRD4ALOX15IRAK4RAB9A | |
| SCHEMBL15926179 | 0.83 | NPSR1 (1.00) | NPSR1ALOX15IRAK4RAB9AMAPT | |
| SCHEMBL9598881 | 0.82 | NPSR1 (0.62) | NPSR1BRD4ALOX15IRAK4RAB9A | |
| SCHEMBL25139435 | 0.78 | CYP1A2 (0.42) | NPSR1BRD4ALOX15MAPTKDM4E | |
| SCHEMBL9298408 | 0.78 | NPSR1 (0.56) | NPSR1BRD4RAB9AKDM4ENPC1 | |
| SCHEMBL9533171 | 0.78 | NPSR1 (0.64) | NPSR1BRD4ALOX15IRAK4RAB9A | |
| SCHEMBL9298650 | 0.78 | NPSR1 (0.47) | NPSR1BRD4ALOX15RAB9AKDM4E | |
| SCHEMBL1596880 | 0.77 | CYP1A2 (0.55) | NPSR1ALOX15RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575614-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992016526-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-01 | — | — | WO | disclosed |