Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067835 | 0.87 | P2RX7 (0.59) | CYP1A2KDM4EALOX15TSHRTDP1 | |
| SCHEMBL30693375 | 0.87 | P2RX7 (0.59) | CYP1A2KDM4EALOX15TSHRTDP1 | |
| SCHEMBL13545046 | 0.87 | CYP1A2 (0.44) | CYP1A2KDM4EALOX15TSHRTDP1 | |
| SCHEMBL801053 | 0.87 | CYP1A2 (0.58) | CYP1A2KDM4ETSHRMAPTSMN1; SMN2 | |
| SCHEMBL6564811 | 0.86 | ALDH1A1 (0.49) | CYP1A2KDM4EALOX15TSHRTDP1 | |
| SCHEMBL19336113 | 0.86 | CYP1A2 (0.43) | CYP1A2KDM4EALOX15TSHRTDP1 | |
| SCHEMBL7262412 | 0.86 | CYP1A2 (0.43) | CYP1A2KDM4EALOX15TSHRTDP1 | |
| SCHEMBL25139435 | 0.84 | CYP1A2 (0.42) | CYP1A2KDM4EALOX15TSHRTDP1 | |
| SCHEMBL21911967 | 0.82 | TERT (0.49) | CYP1A2KDM4EALOX15TSHRTDP1 | |
| SCHEMBL21393426 | 0.82 | CYP1A2 (0.41) | CYP1A2KDM4EALOX15TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295871-A1 | HEPARIN-BASED COMPOSITIONS AND METHODS FOR THE INHIBITION OF METASTASIS | DIAMOND, PAUL | 2012-11-22 | — | — | US | disclosed |
| US-20120049167-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120049167-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20110178104-A1 | Anti-Heparin Compounds | POLYMEDIX INC. (US) | 2011-07-21 | — | — | US | disclosed |
| US-7919562-B2 | Preparation of supramolecular polymers containing sequence-selective hydrogen bonding subunits in their backbone which form double helices | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2011-04-05 | — | — | US | disclosed |
| US-7919562-B2 | Preparation of supramolecular polymers containing sequence-selective hydrogen bonding subunits in their backbone which form double helices | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2011-04-05 | — | — | US | disclosed |
| US-7919562-B2 | Preparation of supramolecular polymers containing sequence-selective hydrogen bonding subunits in their backbone which form double helices | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2011-04-05 | — | — | US | disclosed |
| US-20090318626-A1 | Preparation of supramolecular polymers containing sequence-selective hydrogen bonding subunits in their backbone which form double helices | THE UNIVERSITY OF WESTERN ONTARIO | 2009-12-24 | — | — | US | disclosed |
| US-20090318626-A1 | Preparation of supramolecular polymers containing sequence-selective hydrogen bonding subunits in their backbone which form double helices | THE UNIVERSITY OF WESTERN ONTARIO | 2009-12-24 | — | — | US | disclosed |
| US-20090318626-A1 | Preparation of supramolecular polymers containing sequence-selective hydrogen bonding subunits in their backbone which form double helices | THE UNIVERSITY OF WESTERN ONTARIO | 2009-12-24 | — | — | US | disclosed |
| WO-2007137430-A1 | PREPARATION OF SUPRAMOLECULAR POLYMERS CONTAINING SEQUENCE-SELECTIVE HYDROGEN BONDING SUBUNITS IN THEIR BACKBONE WHICH FORM DOUBLE HELICES | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007137430-A1 | PREPARATION OF SUPRAMOLECULAR POLYMERS CONTAINING SEQUENCE-SELECTIVE HYDROGEN BONDING SUBUNITS IN THEIR BACKBONE WHICH FORM DOUBLE HELICES | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178104-A1 | Anti-Heparin Compounds | SERPINC1, CFH, SERPINH1 | CYP1A2 3934/4885KDM4E 2875/4885ALOX15 2232/4885 |
| US-20120295871-A1 | HEPARIN-BASED COMPOSITIONS AND METHODS FOR THE INHIBITION OF METASTASIS | HPSE, SERPINC1, CD44 | CYP1A2 4412/4885KDM4E 3044/4885ALOX15 2968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.