Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 15/20 | 0.40 |
| ▸ | F10 | P00742 | 15/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642223 | 0.89 | PPARG (0.44) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL9533798 | 0.87 | PPARG (0.41) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL10642627 | 0.86 | PPARG (0.40) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL10636147 | 0.85 | PPARA (0.40) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL9531833 | 0.83 | KDM4E (0.45) | F2F10ITGB3ITGA2B | |
| SCHEMBL10640274 | 0.83 | PPARA (0.36) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL9632602 | 0.82 | PPARA (0.37) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL9533929 | 0.81 | PPARG (0.39) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL10642050 | 0.80 | AKT1 (0.47) | PPARGPPARAPPARDF2 | |
| SCHEMBL9631399 | 0.79 | PPARA (0.36) | PPARGPPARAPPARDF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |