Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632602 | 0.93 | PPARA (0.37) | PPARAPPARGPPARDF2F10 | |
| SCHEMBL10636147 | 0.88 | PPARA (0.40) | PPARAPPARGPPARDF2F10 | |
| SCHEMBL9630834 | 0.86 | KDM4E (0.37) | F2F10ITGB3ITGA2B | |
| SCHEMBL10640311 | 0.85 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL10642223 | 0.84 | PPARG (0.44) | PPARAPPARGPPARDF2F10 | |
| SCHEMBL9632651 | 0.83 | AKT1 (0.37) | PPARAPPARGPPARD | |
| SCHEMBL10640274 | 0.83 | PPARA (0.36) | PPARAPPARGPPARDF2F10 | |
| SCHEMBL10642627 | 0.80 | PPARG (0.40) | PPARAPPARGPPARDF2F10 | |
| SCHEMBL10635622 | 0.79 | F2 (0.36) | PPARGF2F10ITGB3ITGA2B | |
| SCHEMBL9632214 | 0.79 | PPARG (0.37) | PPARAPPARGPPARDF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |