SCHEMBL9531010

SCHEMBL9531010

CCCCc1nc(C(=O)OC)c(Cl)n1Cc1ccc(OCc2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.43
AGTR2 P50052 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9530765 0.92 AGTR1 (0.44) AGTR1AGTR2
SCHEMBL9530283 0.87 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL9532564 0.84 AGTR1 (0.40) AGTR1AGTR2
SCHEMBL9287158 0.83 TLR7 (0.39) AGTR1AGTR2
SCHEMBL9534797 0.82 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL9531203 0.82 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL9041320 0.81 PPARG (0.42)
SCHEMBL9531317 0.81 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL9042890 0.81 PPARG (0.42) AGTR1
SCHEMBL9530983 0.81 PPARG (0.40) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0515548-A4 IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT 1993-03-10 EP disclosed
EP-0515548-A1 IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT MERCK & CO. INC. (US) 1992-12-02 EP disclosed