Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.49 |
| ▸ | PDE5A | O76074 | 6/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531184 | 1.00 | PDE4B (0.49) | PDE4BPDE5APDE3ANPSR1MIF | |
| SCHEMBL9533201 | 0.84 | MAPT (0.44) | PDE4BPDE5APDE3ANPSR1MIF | |
| SCHEMBL9533197 | 0.84 | MAPT (0.44) | PDE4BPDE5APDE3ANPSR1MIF | |
| SCHEMBL3196384 | 0.80 | PDE4B (0.54) | PDE4BPDE5APDE3ANPSR1MIF | |
| SCHEMBL3205869 | 0.74 | PDE4B (0.56) | PDE4BPDE5APDE3ANPSR1MIF | |
| SCHEMBL3205161 | 0.71 | PDE4B (0.53) | PDE4BPDE5APDE3ANPSR1MIF | |
| SCHEMBL3197550 | 0.71 | PDE4B (0.53) | PDE4BPDE5APDE3ANPSR1MIF | |
| SCHEMBL3193018 | 0.71 | PDE4B (0.53) | PDE4BPDE5APDE3ANPSR1MIF | |
| SCHEMBL3185488 | 0.71 | PDE5A (0.50) | PDE4BPDE5APDE3ANPSR1MIF | |
| SCHEMBL3185480 | 0.71 | PDE5A (0.50) | PDE4BPDE5APDE3ANPSR1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270926-B1 | AGENTS PROMOTING THE ACTIVITY OF SOME ANTITUMOR AGENTS AND METHODS FOR THEIR PRODUCTION | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4923871-A | ANTITUMOR | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0270926-A2 | Agents promoting the activity of some antitumor agents and methods for their production | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1988-06-15 | — | — | EP | disclosed |