Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533197 | 1.00 | MAPT (0.44) | MAPTALDH1A1HDAC1NPSR1LMNA | |
| SCHEMBL9531184 | 0.84 | PDE4B (0.49) | MAPTALDH1A1NPSR1LMNAMIF | |
| SCHEMBL9531191 | 0.84 | PDE4B (0.49) | MAPTALDH1A1NPSR1LMNAMIF | |
| SCHEMBL3070035 | 0.72 | HPGD (0.46) | MAPTALDH1A1HDAC1NPSR1LMNA | |
| SCHEMBL5848990 | 0.68 | ALDH1A1 (0.51) | MAPTALDH1A1HDAC1NPSR1MIF | |
| SCHEMBL6526697 | 0.67 | MEN1 (0.56) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6526695 | 0.67 | MEN1 (0.56) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15026365 | 0.67 | MEN1 (0.56) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7384129 | 0.66 | MAPT (0.53) | MAPTALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL17047960 | 0.66 | ALDH1A1 (0.43) | MAPTALDH1A1HDAC1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270926-B1 | AGENTS PROMOTING THE ACTIVITY OF SOME ANTITUMOR AGENTS AND METHODS FOR THEIR PRODUCTION | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4923871-A | ANTITUMOR | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0270926-A2 | Agents promoting the activity of some antitumor agents and methods for their production | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1988-06-15 | — | — | EP | disclosed |