Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729724 | 0.80 | SRC (0.50) | SRCALDH1A1SLC13A5PRMT5WDR77 | |
| SCHEMBL1520555 | 0.79 | SRC (0.51) | SRCALDH1A1KMT2ASLC13A5PRMT5 | |
| SCHEMBL30647012 | 0.79 | SRC (0.51) | SRCALDH1A1KMT2ASLC13A5PRMT5 | |
| SCHEMBL5535285 | 0.77 | SRC (0.50) | SRCSLC13A5MAPTKDM4EADORA2A | |
| SCHEMBL9529628 | 0.77 | NPC1 (0.39) | ALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL3630293 | 0.77 | SRC (0.50) | SRCALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL9410317 | 0.77 | SRC (0.47) | SRCALDH1A1SLC13A5PRMT5WDR77 | |
| SCHEMBL13618688 | 0.76 | SRC (0.41) | SRCALDH1A1KMT2ASLC13A5PRMT5 | |
| SCHEMBL749668 | 0.74 | SRC (0.47) | SRCALDH1A1KMT2ASLC13A5MAPT | |
| SCHEMBL13903229 | 0.74 | SRC (0.47) | SRCKMT2ASLC13A5PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294647-B1 | THIADIAZINONES | MERCK PATENT GmbH (DE) | 1993-07-21 | — | — | EP | disclosed |