Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13347539 | 0.79 | MAPT (0.38) | SMN1; SMN2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL593214 | 0.77 | GAA (0.37) | SRCLMNAHPGDMAPTHTT | |
| SCHEMBL3729724 | 0.76 | SRC (0.50) | SRCALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL9531241 | 0.76 | SRC (0.45) | SRCSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL3630293 | 0.75 | SRC (0.50) | SRCSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL592680 | 0.75 | LIG1 (0.47) | SRCSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL10544590 | 0.75 | AKR1C3 (0.46) | ALDH1A1KMT2AMEN1ATML3MBTL1 | |
| SCHEMBL30647012 | 0.74 | SRC (0.51) | SRCALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL1520555 | 0.74 | SRC (0.51) | SRCALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL6707631 | 0.74 | LTA4H (0.40) | SRCSMN1; SMN2ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401451-B1 | QUINAZOLINE DERIVATIVES WHICH PROMOTE THE RELEASE OF PARATHYROID HORMONE | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |