Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 9/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MPC2 | O95563 | 2/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639049 | 0.90 | CYP3A4 (0.56) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL8021474 | 0.89 | CYP3A4 (0.56) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL10640148 | 0.89 | CYP3A4 (0.55) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL9532695 | 0.88 | CYP3A4 (0.54) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL9532699 | 0.88 | CYP3A4 (0.54) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL9531002 | 0.87 | MEN1 (0.59) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL9531419 | 0.87 | CYP3A4 (0.53) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL9531264 | 0.86 | MEN1 (0.58) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL9531273 | 0.86 | MEN1 (0.58) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL10638937 | 0.85 | ALDH1A1 (0.55) | MAPTCYP3A4MEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |