Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946444 | 0.76 | CA1 (0.49) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL9526738 | 0.73 | DAO (0.41) | KDM4EALDH1A1HPGDLMNAHTT | |
| SCHEMBL9526948 | 0.71 | CA1 (0.43) | KDM4EALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL9528304 | 0.70 | AR (0.42) | KDM4EALDH1A1HPGDMAPK1LMNA | |
| SCHEMBL8946519 | 0.66 | CA1 (0.63) | — | |
| SCHEMBL9526921 | 0.63 | CA1 (0.46) | RPS6KA2 | |
| SCHEMBL5072869 | 0.63 | GSK3B (0.42) | KDM4EALDH1A1HPGDLMNAHTT | |
| SCHEMBL4374361 | 0.63 | CA1 (0.56) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL29370154 | 0.63 | CA1 (0.56) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10019851 | 0.61 | HTR2A (0.57) | KDM4EALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |