Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.49 |
| ▸ | CA2 | P00918 | 7/20 | 0.49 |
| ▸ | CA4 | P22748 | 7/20 | 0.49 |
| ▸ | CA6 | P23280 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526948 | 0.82 | CA1 (0.43) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL8946574 | 0.78 | CA1 (0.65) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL9531322 | 0.76 | KDM4E (0.38) | KDM4EMAPTALDH1A1MEN1HPGD | |
| SCHEMBL9526738 | 0.76 | DAO (0.41) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL9528450 | 0.68 | CA1 (0.41) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL4377821 | 0.68 | DRD2 (0.56) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL6871069 | 0.66 | ROCK2 (0.58) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL2300747 | 0.66 | CA1 (1.00) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL5072869 | 0.66 | GSK3B (0.42) | KDM4EMAPTALDH1A1MEN1HPGD | |
| SCHEMBL4374361 | 0.66 | CA1 (0.56) | CA1CA2CA4CA6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |