Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.49 |
| ▸ | CA2 | P00918 | 10/20 | 0.49 |
| ▸ | CA4 | P22748 | 10/20 | 0.49 |
| ▸ | CA6 | P23280 | 10/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MDH2 | P40926 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946893 | 0.84 | CA1 (0.52) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL8946616 | 0.79 | CA1 (0.56) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL8946305 | 0.76 | CA1 (0.73) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9531330 | 0.73 | CA1 (0.49) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL2294178 | 0.73 | CA1 (0.73) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL8946637 | 0.70 | CA1 (0.54) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9528764 | 0.68 | CA1 (0.53) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL10381644 | 0.68 | CA1 (0.41) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL8946744 | 0.68 | CA1 (0.63) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL8946344 | 0.68 | CA1 (0.49) | CA1CA2CA4CA6CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |