Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.54 |
| ▸ | CA2 | P00918 | 10/20 | 0.54 |
| ▸ | CA4 | P22748 | 10/20 | 0.54 |
| ▸ | CA6 | P23280 | 10/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946893 | 0.83 | CA1 (0.52) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9527581 | 0.80 | CA1 (0.46) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9526921 | 0.80 | CA1 (0.46) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9530865 | 0.79 | CA1 (0.50) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9531330 | 0.78 | CA1 (0.49) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL30251048 | 0.78 | CA1 (0.69) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL4627835 | 0.78 | CA1 (0.69) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL12382594 | 0.75 | CA1 (0.69) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL6277979 | 0.71 | PNMT (0.41) | CA1CA2CA4CA6MAPT | |
| SCHEMBL2298597 | 0.71 | CA1 (1.00) | CA1CA2CA4CA6CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| WO-1990015799-A1 | INDENOINDOLE COMPOUNDS II | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |