Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620987 | 0.82 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AMAPTTP53 | |
| SCHEMBL17620969 | 0.81 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9AMAPTTP53 | |
| SCHEMBL14491526 | 0.78 | HDAC6 (0.50) | ALDH1A1NPC1RAB9AMAPTTP53 | |
| SCHEMBL3601508 | 0.75 | KDM4E (0.53) | ALDH1A1NPC1RAB9AMAPTTP53 | |
| SCHEMBL17620686 | 0.74 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AMAPTTP53 | |
| SCHEMBL8402892 | 0.72 | HDAC6 (0.64) | ALDH1A1NPC1RAB9AMAPTTP53 | |
| SCHEMBL2928930 | 0.72 | KDM4E (0.50) | ALDH1A1NPC1RAB9AMAPTTP53 | |
| SCHEMBL3588603 | 0.71 | MAPT (0.52) | ALDH1A1NPC1RAB9AMAPTTP53 | |
| SCHEMBL16328022 | 0.69 | HDAC6 (0.60) | ALDH1A1NPC1RAB9AMAPTTP53 | |
| SCHEMBL13424021 | 0.68 | HDAC6 (0.58) | ALDH1A1NPC1RAB9AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313458-B1 | IMIDAZO(2,1-B)BENZOTHIAZOLES AND THEIR ACID ADDITION SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-08-11 | — | — | EP | claimed |
| US-4895863-A | MEMORY DISORDERS | ROUSSEL UCLAF (FR) | 1990-01-23 | — | — | US | claimed |
| US-4895863-A | MEMORY DISORDERS | ROUSSEL UCLAF (FR) | 1990-01-23 | — | — | US | disclosed |