Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.47 |
| ▸ | CNR1 | P21554 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531511 | 1.00 | CNR2 (0.47) | CNR2CNR1PPARGPPARDPPARA | |
| SCHEMBL9111856 | 0.86 | ZDHHC20 (0.48) | CNR2CNR1ZDHHC20ZDHHC2MAPT | |
| SCHEMBL9111853 | 0.86 | ZDHHC20 (0.48) | CNR2CNR1ZDHHC20ZDHHC2MAPT | |
| SCHEMBL3701812 | 0.86 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2MAPTHTTEGFR | |
| SCHEMBL3701815 | 0.86 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2MAPTHTTEGFR | |
| SCHEMBL1395631 | 0.83 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2MAPTHTTEGFR | |
| SCHEMBL1395670 | 0.83 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2MAPTHTTEGFR | |
| SCHEMBL4870992 | 0.83 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2MAPTHTTEGFR | |
| SCHEMBL4886505 | 0.80 | CNR1 (0.68) | CNR2CNR1 | |
| SCHEMBL19272321 | 0.80 | CNR2 (0.46) | CNR2CNR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540209-A1 | Imidazole derivatives and pharmaceutical compositions containing the same | THE UPJOHN COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |