Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15801114 | 0.92 | MAPT (0.71) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL17669252 | 0.92 | MAPT (0.71) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL1481892 | 0.87 | POLB (0.72) | KMT2AMAPTALDH1A1CRHBPHTT | |
| SCHEMBL3028108 | 0.85 | MAPT (0.69) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| Acetophenone SCHEMBL28757159 | 0.85 | MAPT (0.64) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL336009 | 0.85 | NPC1 (0.65) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL2327169 | 0.84 | DRD4 (0.66) | KMT2AMAPTALDH1A1LMNATP53 | |
| SCHEMBL1482123 | 0.84 | HTR2A (0.69) | KMT2AMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL909633 | 0.84 | MAPT (0.62) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL15156349 | 0.84 | MAPT (0.62) | NPC1RAB9AKMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961743-B1 | 1-SUBSTITUTED, 4-(SUBSTITUTED PHENOXYMETHYL)-1,2,3-TRIAZOLE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND METHODS FOR PREPARATION THEREOF | FDC LTD (IN) | 2018-06-20 | — | — | EP | disclosed |
| US-7452921-B2 | for use in radiation curing; printing inks or varnishes; 4-Piperazinoacetophenone | SUN CHEMICAL CORPORATION (US) | 2008-11-18 | — | — | US | disclosed |
| US-7452921-B2 | for use in radiation curing; printing inks or varnishes; 4-Piperazinoacetophenone | SUN CHEMICAL CORPORATION (US) | 2008-11-18 | — | — | US | disclosed |
| US-20070066700-A1 | Piperazine-based sensitisers | SUN CHEMICAL CORPORATION | 2007-03-22 | — | — | US | disclosed |
| US-20070066700-A1 | Piperazine-based sensitisers | SUN CHEMICAL CORPORATION | 2007-03-22 | — | — | US | disclosed |
| EP-0250193-B1 | Photoreactive lenses | MARCONI GEC LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| US-4818096-A | SUNGLASSES; BENZO OR NAPHTHOPYRANS WITH NITROGEN CONTAINING SUBSTITUENTS | THE PLESSEY COMPANY PLC (GB) | 1989-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066700-A1 | Piperazine-based sensitisers | H1-4, H1-5, EP300 | NPC1 2729/4885RAB9A 4563/4885KMT2A 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.