Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3483221 | 0.74 | CA2 (0.47) | CA2 | |
| SCHEMBL9529657 | 0.74 | CA2 (0.50) | CA2 | |
| SCHEMBL9531359 | 0.74 | CA2 (0.50) | CA2 | |
| SCHEMBL9372366 | 0.70 | CA2 (0.61) | CA2 | |
| SCHEMBL15009059 | 0.69 | CYP2A6 (0.42) | — | |
| SCHEMBL9372794 | 0.69 | CA2 (0.64) | CA2 | |
| SCHEMBL9530323 | 0.67 | CA2 (1.00) | CA2 | |
| SCHEMBL9372671 | 0.67 | CA2 (0.50) | CA2 | |
| SCHEMBL9529186 | 0.66 | CA2 (0.97) | CA2 | |
| SCHEMBL9529773 | 0.66 | CA2 (1.00) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307084-B1 | Substituted thieno(2,3-b)thiophene-2-sulfonamides as antiglaucoma agents | MERCK & CO INC (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4894390-A | VISION DEFECTS | MERCK & CO., INC. (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0307084-A1 | Substituted thieno(2,3-b)thiophene-2-sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1989-03-15 | — | — | EP | disclosed |
| US-4806562-A | Substituted thieno[2,3-b]thiophene-2-sulfonamides as antiglaucoma agents | MERCK & CO., INC. (US) | 1989-02-21 | — | — | US | disclosed |