Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.51 |
| ▸ | DRD2 | P14416 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233182 | 1.00 | BCHE (0.51) | BCHEDRD2NPC1MLNRNR1I2 | |
| SCHEMBL9531338 | 0.95 | BCHE (0.49) | BCHEDRD2 | |
| SCHEMBL9533489 | 0.93 | BCHE (0.52) | BCHEDRD2NPC1MLNRNR1I2 | |
| SCHEMBL20907013 | 0.93 | ADRA1D (0.47) | BCHEDRD2NPC1MLNRNR1I2 | |
| SCHEMBL9531753 | 0.93 | CHRM2 (0.52) | BCHEDRD2NPC1MLNRNR1I2 | |
| SCHEMBL9533303 | 0.92 | BCHE (0.45) | BCHEDRD2NPC1MLNRNR1I2 | |
| SCHEMBL9532187 | 0.89 | BCHE (0.52) | BCHEDRD2NPC1MLNRNR1I2 | |
| SCHEMBL14367742 | 0.89 | BCHE (0.52) | BCHEDRD2NPC1MLNRNR1I2 | |
| SCHEMBL9533807 | 0.89 | BCHE (0.50) | BCHEDRD2NPC1MLNRNR1I2 | |
| SCHEMBL9531438 | 0.88 | BCHE (0.53) | BCHEDRD2NPC1MLNRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003978-B | The industrialized process for preparing of bepotastine or its racemoid | JIANGSU LIANHUAN PHARMACEUTICAL CO., LTD. (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-104003978-A | Industrial preparation method for bepotastine besilate or racemoid of bepotastine besilate | JIANGSU LIANHUAN PHARMACEUTICAL CO LTD | 2014-08-27 | — | — | CN | claimed |
| US-4929618-A | ANTIALLERGENS, ANTIHISTAMINES | UBE INDUSTRIES, LTD. (JP) | 1990-05-29 | — | — | US | claimed |
| CN-114805302-B | Preparation method of 4- [ (4-chlorophenyl) -2-pyridylmethoxy ] -1-piperidine carboxylic ester | 北京联本医药化学技术有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114805302-A | Preparation method of 4- [ (4-chlorphenyl) -2-pyridylmethoxy ] -1-piperidine carboxylate | 北京联本医药化学技术有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-104003978-B | The industrialized process for preparing of bepotastine or its racemoid | JIANGSU LIANHUAN PHARMACEUTICAL CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-104003978-A | Industrial preparation method for bepotastine besilate or racemoid of bepotastine besilate | JIANGSU LIANHUAN PHARMACEUTICAL CO LTD | 2014-08-27 | — | — | CN | disclosed |
| EP-0335586-B1 | PIPERIDINE & PIPERAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4929618-A | ANTIALLERGENS, ANTIHISTAMINES | UBE INDUSTRIES, LTD. (JP) | 1990-05-29 | — | — | US | disclosed |
| EP-0335586-A1 | Piperidine & piperazine derivatives, process for preparing the same and pharmaceutical compositions containing the same | UBE INDUSTRIES, LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |