Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.75 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.71 |
| ▸ | WDR5 | P61964 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291354 | 0.91 | PTGS2 (0.68) | PTGS2PTGS1ALOX5NPC1LMNA | |
| SCHEMBL6476564 | 0.91 | PTGS2 (0.68) | PTGS2PTGS1ALOX5NPC1LMNA | |
| SCHEMBL6477263 | 0.91 | PTGS2 (0.71) | PTGS2PTGS1ALOX5WDR5 | |
| SCHEMBL6487510 | 0.87 | PTGS2 (1.00) | PTGS2PTGS1ALOX5WDR5 | |
| SCHEMBL6476132 | 0.84 | PTGS2 (0.65) | PTGS2PTGS1ALOX5WDR5ALDH1A1 | |
| SCHEMBL6484222 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6487506 | 0.80 | PTGS2 (0.57) | PTGS2PTGS1ALOX5WDR5ALDH1A1 | |
| SCHEMBL9458601 | 0.80 | PTGS2 (0.57) | PTGS2PTGS1ALOX5ALDH1A1KDM4E | |
| SCHEMBL6997128 | 0.78 | PTGS2 (0.51) | PTGS2PTGS1ALOX5WDR5ALDH1A1 | |
| SCHEMBL6488208 | 0.78 | PTGS2 (0.55) | PTGS2PTGS1ALOX5WDR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852029-B | Method for preparing 2-amino-4, 6-dichloro-5-carboxamido pyrimidine | 苏州开元民生科技股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118852029-A | Method for preparing 2-amino-4, 6-dichloro-5-carboxamido pyrimidine | 苏州开元民生科技股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-113185469-B | Method for modifying photoregulated diaryl dihydrophenazine | 南京先进生物材料与过程装备研究院有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-3959328-A1 | PRODUCTION OF CHEMICALS FROM RENEWABLE SOURCES | Zymochem, Inc. (US) | 2022-03-02 | — | — | EP | disclosed |
| EP-1419160-B1 | METHOD FOR THE PRODUCTION OF 6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZIN-5-YLACETIC ACID | MERCKLE GMBH (DE) | 2008-12-10 | — | — | EP | disclosed |
| EP-0397175-B1 | Substituted pyrrolizine compounds and theit use as pharmaceuticals | DANNHARDT GERD PROF DR (DE) | 1993-12-08 | — | — | EP | disclosed |
| EP-0288196-B1 | Sulfonyldecahydro-8H-isoquino[2,1-g][1,6]naphthyridines, optical isomers thereof and related compounds | SYNTEX (U.S.A.) INC. (US) | 1993-07-28 | — | — | EP | disclosed |
| EP-0524004-A1 | Decahydro-8H-isoquino[2,1-g][1,6]naphthyridine and decahydrobenzo[a]pyrrolo[2,3-e]quinolizine derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| EP-0397175-A1 | Substituted pyrrolizine compounds and theit use as pharmaceuticals | Dannhardt, Gerd, Prof.Dr. (DE) | 1990-11-14 | — | — | EP | disclosed |