Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776026 | 0.80 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1TSHRALDH1A1 | |
| SCHEMBL21883848 | 0.80 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL276565 | 0.79 | — | — | |
| SCHEMBL18391445 | 0.77 | CA1 (0.35) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL7376386 | 0.77 | CA1 (0.35) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL15980616 | 0.77 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1TSHRECE1 | |
| SCHEMBL15980617 | 0.77 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1TSHRECE1 | |
| SCHEMBL3686597 | 0.77 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1TSHRECE1 | |
| SCHEMBL14261122 | 0.73 | SLC1A3 (0.40) | SLC1A3SLC1A2SLC1A1ECE1 | |
| SCHEMBL18594556 | 0.73 | SLC1A3 (0.40) | SLC1A3SLC1A2SLC1A1ECE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543936-A4 | RENIN INHIBITORS | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0543936-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |