Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18391445 | 1.00 | CA1 (0.35) | CA1CA2TSHRALDH1A1LMNA | |
| SCHEMBL22170188 | 0.82 | CA1 (0.38) | CA1CA2TSHREPHX1SLC1A3 | |
| SCHEMBL22593906 | 0.81 | LMNA (0.36) | TSHRALDH1A1LMNAENPEPGABRR1 | |
| SCHEMBL18554189 | 0.81 | LMNA (0.36) | TSHRALDH1A1LMNAENPEPGABRR1 | |
| SCHEMBL28006990 | 0.80 | TSHR (0.38) | CA1TSHRALDH1A1LMNAGAA | |
| SCHEMBL9611232 | 0.79 | GABRR1 (0.38) | CA1CA2LMNAEPHX1SLC1A3 | |
| SCHEMBL3325557 | 0.78 | NAALAD2 (0.45) | TSHRALDH1A1LMNAGAAPKM | |
| SCHEMBL13969782 | 0.78 | NAALAD2 (0.45) | TSHRALDH1A1LMNAGAAPKM | |
| SCHEMBL17335573 | 0.78 | CA1 (0.37) | CA1CA2TSHREPHX1SLC1A3 | |
| SCHEMBL12463915 | 0.78 | NAALAD2 (0.45) | TSHRALDH1A1LMNAGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383635-A2 | Peptides having renin inhibitory activity their preparation and use | Sankyo Company Limited (JP) | 1990-08-22 | — | — | EP | claimed |