Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | AGER | Q15109 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9527666 | 0.99 | KMT2A (0.53) | MEN1KMT2AAGERHRH3MAOB | |
| SCHEMBL9372937 | 0.93 | MEN1 (0.50) | MEN1KMT2AKDM4ETDP1NPC1 | |
| Oxalic Acid SCHEMBL9368390 | 0.89 | KMT2A (0.56) | MEN1KMT2AHRH3KDM4ETDP1 | |
| SCHEMBL9697715 | 0.87 | MEN1 (0.53) | MEN1KMT2AHRH3MAOBACHE | |
| Hydrochloric Acid SCHEMBL9528941 | 0.86 | MEN1 (0.52) | MEN1KMT2AHRH3MAOBACHE | |
| SCHEMBL9527998 | 0.86 | MEN1 (0.51) | MEN1KMT2AAGERHRH3MAOB | |
| SCHEMBL9698285 | 0.84 | HRH3 (0.54) | MEN1KMT2AHRH3MAOBKDM4E | |
| SCHEMBL9531944 | 0.84 | HRH3 (0.61) | HRH3CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Oxalic Acid SCHEMBL9531846 | 0.83 | HRH3 (0.64) | MEN1KMT2AHRH3CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL9527566 | 0.83 | HRH3 (0.53) | MEN1KMT2AHRH3MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542844-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | claimed |
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |