Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9527566 | 0.99 | HRH3 (0.53) | HRH3MAOBMEN1KMT2AKDM4E | |
| SCHEMBL9698304 | 0.87 | HRH3 (0.45) | HRH3MAOB | |
| Hydrochloric Acid SCHEMBL27351881 | 0.86 | HRH3 (0.44) | HRH3MAOB | |
| SCHEMBL9527998 | 0.86 | MEN1 (0.51) | HRH3MAOBMEN1KMT2A | |
| SCHEMBL9532493 | 0.84 | MEN1 (0.54) | HRH3MAOBMEN1KMT2AKDM4E | |
| SCHEMBL9531944 | 0.84 | HRH3 (0.61) | HRH3 | |
| Hydrochloric Acid SCHEMBL9527666 | 0.83 | KMT2A (0.53) | HRH3MAOBMEN1KMT2AKDM4E | |
| SCHEMBL13761565 | 0.82 | DRD2 (0.52) | HRH3MAOBMEN1KMT2AKDM4E | |
| SCHEMBL9527422 | 0.82 | KDM4E (0.54) | HRH3KDM4E | |
| SCHEMBL9528653 | 0.82 | HRH3 (0.53) | HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |