SCHEMBL9532550

SCHEMBL9532550

CC(F)(F)Oc1[c]cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6593656 0.84
SCHEMBL746777 0.84
SCHEMBL80520 0.83 KIF11 (0.31)
SCHEMBL49983 0.83 KIF11 (0.31)
SCHEMBL9325480 0.81
SCHEMBL9030688 0.79
SCHEMBL1008473 0.79
SCHEMBL9528791 0.79
SCHEMBL15271374 0.79
SCHEMBL7460444 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862691-B2 Cyclic triazo and diazo sodium channel blockers UNIVERSITY OF GREENWICH (GB) 2018-01-09 US claimed
US-20160311784-A1 CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS UNIVERSITY OF GREENWICH (GB) 2016-10-27 US claimed
CN-108794461-B Fluorine-containing phenyl oxadiazole pyrazole insecticidal bactericide 青岛科技大学 2021-03-09 CN disclosed
CN-108794462-B Oxadiazole insecticidal bactericide containing fluorine cyanimine thiazolidine substituent 青岛科技大学 2021-02-19 CN disclosed
CN-104379574-B For suppressing the heterocyclic carbamate derivatives of the activity of ABL1, ABL2 and BCR ABL1 诺华股份有限公司 2017-03-01 CN disclosed
EP-0320733-B1 2-TERT.-BUTYL-5-ISOXAZOLYL METHYLTHIO-3(2H)-PYRIDAZIN-3-ONE DERIVATIVES BASF Aktiengesellschaft (DE) 1993-03-03 EP disclosed
US-4929617-A INSECTICIDES, MITICIDES BASF AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
EP-0351589-A2 3(2H)-Pyridazinone derivatives for controlling snails BASF Aktiengesellschaft (DE) 1990-01-24 EP disclosed