Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854283 | 1.00 | MEN1 (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL9386704 | 1.00 | MEN1 (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL11333828 | 1.00 | MEN1 (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL8455284 | 1.00 | MEN1 (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL8499290 | 1.00 | MEN1 (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL6901492 | 1.00 | MEN1 (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL11577648 | 1.00 | MEN1 (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL2909988 | 1.00 | MEN1 (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL3346302 | 0.98 | MEN1 (0.48) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL6906272 | 0.95 | MEN1 (0.48) | MEN1KMT2AKDM4CL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251827-B1 | NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0261254-B1 | 3,4-DIHYDRO-4-OXO-2H-1-BENZOPYRANYLOXY ALKANOIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0261254-A1 | 3,4-Dihydro-4-oxo-2H-1-benzopyranyloxy alkanoic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-30 | — | — | EP | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4650812-A | ANTIALLERGY | HOFFMANN-LA ROCHE INC. (US) | 1987-03-17 | — | — | US | disclosed |
| US-4325967-A | Cyclopentane derivatives | MAY & BAKER LIMITED (GB) | 1982-04-20 | — | — | US | disclosed |
| US-4296042-A | Preparation of unsaturated aliphatic insect pheromones using cyclic phosphonium ylids | SYNTEX (U.S.A.) INC. (US) | 1981-10-20 | — | — | US | disclosed |
| US-4183870-A | Cyclopentane derivatives | MAY & BAKER LIMITED (GB) | 1980-01-15 | — | — | US | disclosed |
| US-4171375-A | Cyclopentane derivatives and their pharmaceutical compositions | MAY & BAKER LIMITED (GB) | 1979-10-16 | — | — | US | disclosed |