Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.67 |
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | NAAA | Q02083 | 3/20 | 0.55 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.55 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.55 |
| ▸ | PRCP | P42785 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5933219 | 1.00 | EPHX1 (0.67) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL9533596 | 1.00 | EPHX1 (0.67) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL5932722 | 1.00 | EPHX1 (0.67) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL690004 | 1.00 | EPHX1 (0.67) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL5932682 | 1.00 | EPHX1 (0.67) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL5932852 | 1.00 | EPHX1 (0.67) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL690225 | 0.98 | — | — | |
| SCHEMBL687620 | 0.90 | — | — | |
| SCHEMBL9615037 | 0.87 | KDM4E (0.52) | EPHX1CASP2 | |
| SCHEMBL12807564 | 0.87 | KDM4E (0.52) | EPHX1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251827-B1 | NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |