Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807564 | 1.00 | KDM4E (0.52) | KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL5932722 | 0.87 | EPHX1 (0.67) | EPHX1CASP2 | |
| SCHEMBL5933219 | 0.87 | EPHX1 (0.67) | EPHX1CASP2 | |
| SCHEMBL5932852 | 0.87 | EPHX1 (0.67) | EPHX1CASP2 | |
| SCHEMBL690004 | 0.87 | EPHX1 (0.67) | EPHX1CASP2 | |
| SCHEMBL9532818 | 0.87 | EPHX1 (0.67) | EPHX1CASP2 | |
| SCHEMBL9533596 | 0.87 | EPHX1 (0.67) | EPHX1CASP2 | |
| SCHEMBL5932682 | 0.87 | EPHX1 (0.67) | EPHX1CASP2 | |
| SCHEMBL10508380 | 0.87 | KDM4E (0.42) | KDM4EMAPK1HIF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL11515820 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517881-A1 | BITUMEN/POLYMER COMPONENT GIVING BITUMEN/POLYMER COMPOSITIONS WITH VERY LOW HEAT SENSITIVITY FOR USE IN SURFACING. | ELF FRANCE (FR) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992011321-A2 | BITUMEN/POLYMER COMPONENT GIVING BITUMEN/POLYMER COMPOSITIONS WITH VERY LOW HEAT SENSITIVITY FOR USE IN SURFACING | ELF FRANCE (FR) | 1992-07-09 | — | — | WO | disclosed |