Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554165 | 0.94 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9036172 | 0.94 | AGTR1 (0.63) | AGTR1AGTR2PPARG | |
| SCHEMBL9533795 | 0.94 | PPARG (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL9532126 | 0.94 | PPARG (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL9530481 | 0.93 | AGTR1 (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL9532945 | 0.93 | PPARG (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL9554104 | 0.91 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL9536510 | 0.91 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL9036057 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9533921 | 0.89 | AGTR1 (0.57) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238952-A | Treating glaucoma disorders | G. D. SEARLE & CO. (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0555331-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. | SEARLE & CO (US) | 1993-08-18 | — | — | EP | disclosed |
| US-5087634-A | N-substituted imidazol-2-one compounds for treatment of circulatory disorders | G. D. SEARLE & CO. (US) | 1992-02-11 | — | — | US | disclosed |