Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.63 |
| ▸ | PPARG | P37231 | 6/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072226 | 0.77 | FFAR1 (0.77) | FFAR1PPARGTSHRHRH3ALDH1A1 | |
| SCHEMBL29547028 | 0.77 | FFAR1 (1.00) | FFAR1PPARGHRH3PPARA | |
| SCHEMBL291967 | 0.77 | FFAR1 (1.00) | FFAR1PPARGHRH3PPARA | |
| SCHEMBL9143087 | 0.76 | FFAR1 (0.64) | FFAR1PPARGRAB9AHRH3HPGD | |
| SCHEMBL9570670 | 0.76 | FFAR1 (0.71) | FFAR1PPARGTSHRHRH3ALDH1A1 | |
| SCHEMBL6477400 | 0.75 | TSHR (0.62) | PPARGTSHRRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6476905 | 0.75 | TSHR (0.62) | FFAR1TSHRRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8129853 | 0.75 | PPARG (0.62) | FFAR1PPARGHRH3PPARA | |
| SCHEMBL9570560 | 0.75 | FFAR1 (0.69) | FFAR1PPARGTSHRHRH3ALDH1A1 | |
| SCHEMBL8957444 | 0.75 | FFAR1 (0.69) | FFAR1PPARGTSHRHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555251-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | claimed |
| WO-1992007838-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | claimed |