Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725332 | 0.81 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL725331 | 0.81 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL3335215 | 0.79 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL3335212 | 0.79 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL23169396 | 0.78 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL22901815 | 0.78 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL16825840 | 0.75 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL16825841 | 0.75 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL25537950 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTHTTMEN1 | |
| SCHEMBL376626 | 0.72 | MAPT (1.00) | ALDH1A1KDM4EMAPTHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377528-B1 | Piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA (FR) | 1993-12-08 | — | — | EP | disclosed |
| US-5001134-A | Piperidines, processes of preparation and medications containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1991-03-19 | — | — | US | disclosed |
| EP-0377528-A1 | Piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-07-11 | — | — | EP | disclosed |