Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL5029537 | 0.98 | TDP1 (0.37) | TDP1SMN1; SMN2CHRM1AKR1A1CHRM3 | |
| Propane SCHEMBL28210014 | 0.91 | TDP1 (0.39) | TDP1SMN1; SMN2CHRM1AKR1A1CHRM3 | |
| SCHEMBL740786 | 0.91 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL28865271 | 0.91 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL10538382 | 0.91 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL8852601 | 0.91 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL10777605 | 0.91 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL187913 | 0.91 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL3133461 | 0.91 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL10782749 | 0.91 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550652-A1 | DETERGENT COMPOSITIONS CONTAINING ALKYL ETHOXY CARBOZYLATES AND POLYHYDROXY FATTY ACID AMIDES. | PROCTER & GAMBLE (US) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006157-A1 | DETERGENT COMPOSITIONS CONTAINING ALKYL ETHOXY CARBOZYLATES AND POLYHYDROXY FATTY ACID AMIDES | THE PROCTER & GAMBLE COMPANY (US) | 1992-04-16 | — | — | WO | disclosed |