Alcohol

Alcohol

SCHEMBL5029537

CCO.O=C(O)CC(C(=O)O)S(=O)(=O)O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
CHRM1 P11229 1/20 0.34
AKR1A1 P14550 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34
DRD3 P35462 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.33
RECQL P46063 1/20 0.33
MME P08473 2/20 0.33
FFAR3 O14843 1/20 0.32
GPR84 Q9NQS5 4/20 0.31
FOLH1 Q04609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL9533581 0.98 TDP1 (0.36) TDP1SMN1; SMN2CHRM1AKR1A1CHRM3
Propane SCHEMBL28210014 0.93 TDP1 (0.39) TDP1SMN1; SMN2CHRM1AKR1A1CHRM3
Butane SCHEMBL613013 0.91 TDP1 (0.39) TDP1SMN1; SMN2CHRM1AKR1A1CHRM3
Butane SCHEMBL17925315 0.91 TDP1 (0.39) TDP1SMN1; SMN2CHRM1AKR1A1CHRM3
Propionic Acid SCHEMBL28423676 0.91 FFAR3 (0.43) TDP1SMN1; SMN2CHRM1AKR1A1CHRM3
Butanedione SCHEMBL27091933 0.91 TDP1 (0.37) TDP1SMN1; SMN2CHRM1AKR1A1CHRM3
Ethane SCHEMBL28213012 0.91 TDP1 (0.40) TDP1SMN1; SMN2CHRM1AKR1A1CHRM3
SCHEMBL987086 0.91 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL10698543 0.91 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL11360544 0.91 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947711-B Preparation method of fatty alcohol sulfosuccinic acid monoester disodium salt 广州宏度精细化工有限公司 2024-02-09 CN claimed
CN-117126350-A Nano modified transparent waterproof repair emulsion and preparation method thereof 浙江科力森化学有限公司 2023-11-28 CN claimed
CN-116947711-A Preparation method of fatty alcohol sulfosuccinic acid monoester disodium salt 广州宏度精细化工有限公司 2023-10-27 CN claimed
CN-113372854-A Thin-coating high-viscosity water-based polyacrylate pressure-sensitive adhesive and preparation method and application thereof 襄阳三沃航天薄膜材料有限公司 2021-09-10 CN claimed
CN-111087328-A Preparation method of fatty alcohol sulfosuccinic acid monoester disodium salt 广州宏茂实业有限公司 2020-05-01 CN claimed
CN-110945111-A Soap block 巴斯夫欧洲公司 2020-03-31 CN claimed
CN-116947711-B Preparation method of fatty alcohol sulfosuccinic acid monoester disodium salt 广州宏度精细化工有限公司 2024-02-09 CN disclosed
CN-116947711-B Preparation method of fatty alcohol sulfosuccinic acid monoester disodium salt 广州宏度精细化工有限公司 2024-02-09 CN disclosed
CN-116947711-B Preparation method of fatty alcohol sulfosuccinic acid monoester disodium salt 广州宏度精细化工有限公司 2024-02-09 CN disclosed
CN-117126350-A Nano modified transparent waterproof repair emulsion and preparation method thereof 浙江科力森化学有限公司 2023-11-28 CN disclosed
CN-116947711-A Preparation method of fatty alcohol sulfosuccinic acid monoester disodium salt 广州宏度精细化工有限公司 2023-10-27 CN disclosed
CN-116947711-A Preparation method of fatty alcohol sulfosuccinic acid monoester disodium salt 广州宏度精细化工有限公司 2023-10-27 CN disclosed
CN-116947711-A Preparation method of fatty alcohol sulfosuccinic acid monoester disodium salt 广州宏度精细化工有限公司 2023-10-27 CN disclosed
CN-107375019-A AQUEOUS COSMETIC COMPOSITION COMPRISING ALKYLCELLULOSE 欧莱雅 2017-11-24 CN disclosed
CN-104059222-B A kind of double bond containing alcohol ether and production method thereof SHANGHAI HONESTY FINE CHEMICAL CO., LTD. (CN) 2016-11-30 CN disclosed
CN-103224622-B A kind of double bond containing alcohol ether sulfuric ester or salt and production method thereof SHANGHAI YOUCHUANG CHEMICAL PRODUCT CO., LTD. (CN) 2016-05-18 CN disclosed
CN-105001127-A Guerbet alcohol sulfosuccinic acid monoester disodium salt and preparation method thereof CHINA RES INST DAILY CHEM IND 2015-10-28 CN disclosed
CN-105001127-A Guerbet alcohol sulfosuccinic acid monoester disodium salt and preparation method thereof CHINA RES INST DAILY CHEM IND 2015-10-28 CN disclosed
CN-104059222-A Alcohol ether containing double bond and production method thereof SHANGHAI HONESTY FINE CHEMICAL TECHNOLOGY CO LTD 2014-09-24 CN disclosed
US-20080200358-A1 Oiling Agent for Fiber Treatment SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2008-08-21 US disclosed