Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216380 | 0.78 | MAPT (0.59) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL20282082 | 0.75 | MAPT (0.55) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL61427 | 0.74 | MAPT (0.48) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL3503925 | 0.71 | KMT2A (1.00) | MAPTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL15716688 | 0.71 | KMT2A (1.00) | MAPTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL23056136 | 0.66 | ALDH1A1 (0.48) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL12814059 | 0.65 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL15573003 | 0.65 | MAPT (0.41) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL15268200 | 0.65 | MAPT (0.47) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL3189454 | 0.64 | MAPT (0.46) | MAPTGAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118186779-A | Sizing agent for enhancing PBO fiber composite material interface, and preparation method and application thereof | 中国科学院化学研究所 | 2024-06-14 | — | — | CN | disclosed |
| EP-0348872-B1 | FUSED DIHYDROXYQUINOXALINES AND THEIR USE AS GLUTAMATE ANTAGONISTS | NOVO NORDISK A/S (DK) | 1993-09-29 | — | — | EP | disclosed |
| US-5109001-A | Treating hyperactivity of excitatory neurotransmitters | NOVO NORDISK A/S (DK) | 1992-04-28 | — | — | US | disclosed |
| US-5079250-A | TRICYCLIC HETEROCYCLIC DIOLS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-01-07 | — | — | US | disclosed |
| US-5075306-A | Nervous system, psychological disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| US-5057516-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-10-15 | — | — | US | disclosed |
| US-4977155-A | Nervous system disorders | A/S FERROSAN (DK) | 1990-12-11 | — | — | US | disclosed |