Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687806 | 0.73 | KMT2A (0.44) | ALDH1A1KMT2ARAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL10692329 | 0.66 | KMT2A (0.47) | ALDH1A1KMT2ARAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL669626 | 0.65 | KMT2A (0.54) | ALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL669851 | 0.65 | CES1 (0.61) | CES1ALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL26809469 | 0.65 | HTT (0.54) | ALDH1A1KMT2ASMN1; SMN2MAPK1CA12 | |
| SCHEMBL5545766 | 0.65 | CYP1A2 (0.41) | ALDH1A1KMT2ARAB9ASMN1; SMN2CA12 | |
| SCHEMBL28274371 | 0.63 | CES1 (0.48) | CES1ALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL132067 | 0.63 | CES1 (0.58) | CES1ALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL11183801 | 0.63 | CES1 (0.58) | CES1ALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| Water SCHEMBL2479676 | 0.63 | CES1 (0.58) | CES1ALDH1A1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252744-B1 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | LILLY CO ELI (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4734498-A | 3β-succinimidoazetidinones as chiral intermediates | ELI LILLY AND COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0252744-A2 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |