Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687806 | 0.88 | KMT2A (0.44) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL9533869 | 0.74 | GLA (0.35) | POLB | |
| SCHEMBL28501745 | 0.71 | LMNA (0.54) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL133554 | 0.70 | KMT2A (0.53) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL19309377 | 0.70 | KMT2A (0.53) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL28706308 | 0.68 | LMNA (0.61) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL25263447 | 0.68 | KMT2A (0.50) | KMT2AF2LMNAMAPK1TSHR | |
| Benzoyl Peroxide SCHEMBL1315923 | 0.68 | F2 (0.61) | KMT2AF2LMNAMAPK1TSHR | |
| Benzoyl Peroxide SCHEMBL1315128 | 0.68 | F2 (0.61) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL28771494 | 0.68 | KMT2A (0.47) | KMT2AF2LMNAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252744-A2 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |