Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26193070 | 0.83 | KMT2A (0.46) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL22249428 | 0.81 | KMT2A (0.44) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL28647464 | 0.78 | HPGD (0.48) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL10520741 | 0.78 | ABCB1 (0.47) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL28739774 | 0.77 | CYP3A4 (0.50) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL31140205 | 0.77 | MAOB (0.53) | PPARGKDM4ECSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL8786379 | 0.76 | ABCB1 (0.45) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL29799485 | 0.76 | MAOB (0.52) | KDM4ECSNK2A2CSNK2BCSNK2A1LMNA | |
| SCHEMBL4657823 | 0.76 | NPC1 (0.54) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL11452110 | 0.75 | KCNA3 (0.65) | MAOBNPC1CA12CA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525123-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES. | UPJOHN CO (US) | 1993-02-03 | — | — | EP | claimed |