Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26661262 | 0.99 | MAOB (0.51) | MAOBFAAHMGLLMAPTKDM4E | |
| SCHEMBL26661266 | 0.99 | MAOB (0.51) | MAOBFAAHMGLLMAPTKDM4E | |
| SCHEMBL17237794 | 0.99 | MAOB (0.51) | MAOBFAAHMGLLMAPTKDM4E | |
| SCHEMBL31140205 | 0.95 | MAOB (0.53) | MAOBMAPTKDM4ELMNAHPGD | |
| SCHEMBL8786379 | 0.85 | ABCB1 (0.45) | MAOBMAPTKDM4ELMNAHPGD | |
| SCHEMBL10520741 | 0.85 | ABCB1 (0.47) | MAOBMAPTKDM4ELMNAHPGD | |
| SCHEMBL28647464 | 0.79 | HPGD (0.48) | MAOBMAPTKDM4ELMNAHPGD | |
| SCHEMBL16534423 | 0.78 | FAAH (0.44) | MAOBFAAHMGLLKDM4ELMNA | |
| SCHEMBL29627455 | 0.78 | CYP3A4 (0.45) | MAOBMAPTKDM4ELMNAHPGD | |
| SCHEMBL8782562 | 0.78 | HPGD (0.55) | MAPTKDM4ELMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240292837-A1 | CHROMONE DERIVATIVES AS ATTRACTANTS AND REPELLENTS OF BLOOD-SUCKING, BITING INVERTEBRATES | INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT (FR) | 2024-09-05 | — | — | US | disclosed |
| EP-4280877-A1 | CHROMONE DERIVATIVES AS ATTRACTANTS AND REPELLENTS OF BLOOD-SUCKING, BITING INVERTEBRATES | Centre National de la Recherche Scientifique (FR) | 2023-11-29 | — | — | EP | disclosed |
| WO-2022157118-A1 | CHROMONE DERIVATIVES AS ATTRACTANTS AND REPELLENTS OF BLOOD-SUCKING, BITING INVERTEBRATES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240292837-A1 | CHROMONE DERIVATIVES AS ATTRACTANTS AND REPELLENTS OF BLOOD-SUCKING, BITING INVERTEBRATES | C3AR1, C5AR1, CCR5 | MAOB 1070/4885FAAH 3007/4885MGLL 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.