SCHEMBL9534069

SCHEMBL9534069

O=COCCN1CCSCC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.32
GAA P10253 1/20 0.31
ARG1 P05089 1/20 0.30
ARG2 P78540 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20407546 0.84
SCHEMBL27746939 0.80
SCHEMBL64778 0.80 HRH3 (0.39)
SCHEMBL4776536 0.79 KDM4E (0.30)
SCHEMBL28110383 0.78 HRH3 (0.42)
SCHEMBL271825 0.78 HRH3 (0.42)
SCHEMBL5946047 0.77 ALDH1A1 (0.37)
Hydrochloric Acid SCHEMBL27699271 0.77 HRH3 (0.41)
SCHEMBL197295 0.75 GLA (0.42)
SCHEMBL27574064 0.75 HSD17B10 (0.40) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539372-A1 THERAPEUTIC AGENTS The Boots Company PLC (GB) 1993-05-05 EP disclosed
WO-1991011448-A1 THERAPEUTIC AGENTS THE BOOTS COMPANY PLC (GB) 1991-08-08 WO disclosed
US-5032606-A Novel fluorinated resorcinol ethers and their use as anti-allergics and anti-inflammatories CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4863942-A Novel resorcinol ethers and anti-inflammatory and anti-allergic use thereof CIBA-GEIGY CORPORATION (US) 1989-09-05 US disclosed
US-4820726-A Oxaloamino substituted fluorinated resorcinol ethers and anti-allergic and anti-inflammatory use thereof CIBA-GEIGY CORPORATION (US) 1989-04-11 US disclosed
US-4670604-A Novel fluorinated resorcinol ethers CIBA-GEIGY CORPORATION (US) 1987-06-02 US disclosed
EP-0222961-A1 Resorcinol ethers CIBA-GEIGY AG (CH) 1987-05-27 EP disclosed
EP-0165897-A2 Resorcin ethers CIBA-GEIGY AG (CH) 1985-12-27 EP disclosed