Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9536477 | 0.99 | CA2 (0.64) | CA2 | |
| SCHEMBL9533435 | 0.78 | CA2 (1.00) | CA2 | |
| SCHEMBL9534631 | 0.78 | CA2 (1.00) | CA2 | |
| Hydrochloric Acid SCHEMBL9534585 | 0.77 | CA2 (1.00) | CA2 | |
| Hydrochloric Acid SCHEMBL9535111 | 0.77 | CA2 (1.00) | CA2 | |
| SCHEMBL9534274 | 0.76 | CA2 (1.00) | CA2 | |
| Hydrochloric Acid SCHEMBL9536472 | 0.75 | CA2 (1.00) | CA2 | |
| SCHEMBL9533926 | 0.68 | CA2 (1.00) | CA2 | |
| Hydrochloric Acid SCHEMBL9538479 | 0.67 | CA2 (1.00) | CA2 | |
| SCHEMBL9529762 | 0.66 | CA2 (0.58) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375320-B1 | Substituted thieno(3,2-B) thiophene-2-sulfonamides as topically active carbonic anhydrase inhibitors | MERCK & CO INC (US) | 1993-11-24 | — | — | EP | disclosed |
| EP-0375320-A1 | Substituted thieno(3,2-B) thiophene-2-sulfonamides as topically active carbonic anhydrase inhibitors | MERCK & CO. INC. (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4876271-A | GLAUCOMA | MERCK & CO., INC. (US) | 1989-10-24 | — | — | US | disclosed |