⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416020 | 0.81 | — | — | |
| SCHEMBL179841 | 0.81 | CYP2D6 (0.32) | — | |
| SCHEMBL20661653 | 0.81 | — | — | |
| SCHEMBL7142061 | 0.81 | CYP2D6 (0.32) | — | |
| SCHEMBL439582 | 0.79 | — | — | |
| SCHEMBL12022881 | 0.77 | FDPS (0.41) | — | |
| SCHEMBL20908243 | 0.75 | — | — | |
| SCHEMBL190387 | 0.75 | — | — | |
| SCHEMBL22570000 | 0.74 | — | — | |
| SCHEMBL20306158 | 0.74 | FDPS (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324109-B1 | 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5023253-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0324109-A2 | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-07-19 | — | — | EP | disclosed |
| WO-1989005811-A1 | NEW 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1989-06-29 | — | — | WO | disclosed |