⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL4013439 | 0.80 | LDHA (0.75) | — | |
| Malonic Acid SCHEMBL27656392 | 0.80 | LDHA (0.75) | — | |
| Malonic Acid SCHEMBL9240906 | 0.80 | LDHA (0.75) | — | |
| Malonic Acid SCHEMBL28539575 | 0.80 | LDHA (0.75) | — | |
| SCHEMBL35749 | 0.77 | — | — | |
| Acetoacetic Acid SCHEMBL10941648 | 0.77 | LDHA (0.57) | — | |
| SCHEMBL6647502 | 0.77 | LDHA (0.57) | — | |
| Malonic Acid SCHEMBL11075854 | 0.77 | LDHA (0.69) | — | |
| Acetoacetic Acid SCHEMBL1406366 | 0.77 | LDHA (0.57) | — | |
| Acetoacetic Acid SCHEMBL1144213 | 0.77 | LDHA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 482 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3683221-B1 | NOVEL CHLORIN E6 DERIVATIVE AND PHARMACEUTICALLY-ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SHANGHAI BIOPHY BIOLOGICAL PHARMACEUTICAL CO LTD (CN) | 2023-06-28 | — | — | EP | claimed |
| EP-3727390-B1 | MTOR INHIBITORS | GALDERMA RES & DEV (FR) | 2023-03-22 | — | — | EP | claimed |
| CN-113527319-B | Novel chlorin e4 derivative and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国人民解放军海军军医大学 | 2023-03-07 | — | — | CN | claimed |
| US-11518767-B2 | MTOR inhibitor compounds | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2022-12-06 | — | — | US | claimed |
| CN-113527319-A | Novel chlorin e4Derivative and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国人民解放军海军军医大学 | 2021-10-22 | — | — | CN | claimed |
| US-20200317683-A1 | MTOR INHIBITOR COMPOUNDS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-10-08 | — | — | US | claimed |
| CN-107987081-B | Chlorin e6 derivative and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 刘辉 | 2019-12-06 | — | — | CN | claimed |
| CN-107987081-A | A kind of new chlorin e 6 derivative and its pharmaceutically acceptable salt, its preparation method and application | 刘辉 | 2018-05-04 | — | — | CN | claimed |
| WO-2017064156-A1 | NOVEL 6-FUSED AND 2-HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2017-04-20 | — | — | WO | claimed |
| EP-1867645-B1 | Variolin derivatives and their use as antitumor agents | PHARMA MAR SA (ES) | 2010-09-08 | — | — | EP | claimed |
| CN-1127492-C | Antirheumatic | SHIONOJI & CO LTD (JP) | 2003-11-12 | — | — | CN | claimed |
| US-20030125364-A1 | Antirheumatic agent | MATSUMOTO SAICHI (JP) | 2003-07-03 | — | — | US | claimed |
| US-6583305-B1 | Catalysts for enantioselective hydrogenation, hydroboration or 1,4 addition of olefins, ketones and imines | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-06-24 | — | — | US | claimed |
| EP-1109819-B1 | FERROCENE-BASED DIPHOSPHONITES FOR ASYMMETRICAL CATALYSIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-04-16 | — | — | EP | claimed |
| WO-2003006457-A1 | VARIOLIN DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | PHARMA MAR, S.A. (ES) | 2003-01-23 | — | — | WO | claimed |
| EP-1109794-A1 | AZA-CYCLODEPSIPEPTIDES AND THEIR USE AS ANTIPARASITICS | BAYER AG (DE) | 2001-06-27 | — | — | EP | claimed |
| US-6232324-B1 | AS HYPERTENSIVE AGENTS FOR DIALYSIS INDUCED HYPOTENSION; ADMINISTERING COMPOUNDS SUCH AS 1-(3-(2-PHENYLPYRAZOLO(1,5-A) PYRIDIN-3-YL)ACRYLOYL)-2-(CARBOXY METHYL)PIPERIDINE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | claimed |
| CN-1283194-A | Antirheumatic | SHIONOJI & CO LTD (JP) | 2001-02-07 | — | — | CN | claimed |
| EP-1026162-A1 | ANTIRHEUMATIC | SHIONOGI & CO., LTD. (JP) | 2000-08-09 | — | — | EP | claimed |
| WO-2000014079-A1 | AZA-CYCLODEPSIPEPTIDES AND THEIR USE AS ANTIPARASITICS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-16 | — | — | WO | claimed |